The Science Behind MUTO

A unique, multi-pathway formula designed to slow biological ageing.


Ageing is not driven by a single process.


It reflects progressive changes across cellular energy production, oxidative protection, inflammation signalling, metabolic efficiency, DNA integrity and cellular renewal.


MUTO is formulated around this biological reality.
Rather than targeting one mechanism in isolation, MUTO is built as a multi-pathway system, supporting six core cellular complexes that collectively influence healthspan and long-term cellular function.

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BUILT BY SCIENCE.
LED BY EXPERIENCE.

Meet the Founder.


MUTO was founded and formulated by Dr Richie Barclay, PhD - a longevity and cellular ageing researcher with over 15 years of experience in human nutrition, metabolic health and applied longevity science.


Dr Barclay’s work bridges academic research, clinical practice and real-world application. Rather than chasing trends or single-compound solutions, MUTO was built to reflect how ageing actually works at a biological level - complex, multi-factorial and deeply interconnected.

Every formulation decision within MUTO reflects this philosophy:

  • Evidence before marketing
  • Mechanism before claims
  • Clinical relevance over novelty

MUTO is not designed to impress. It is designed to work.

LEARN MORE

OUR CELLULAR APPROACH

Ageing is multi-pathway. Effective support should be too.


Most supplements focus narrowly on one aspect of ageing — often NAD+ alone or antioxidant support in isolation.


Human biology does not operate in silos.
Cellular ageing reflects interconnected systems, where improvements in one pathway depend on stability across others. MUTO is designed to support this networked biology through six foundational pathways that collectively influence healthspan.

THE SCIENCE BEHIND 
CELLULAR AGEING

Understanding the interconnected cellular systems that drive ageing and long-term resilience.

Ageing is influenced by interconnected biological systems - from mitochondrial efficiency to inflammation, oxidative stress and cellular turnover. Supporting these pathways helps maintain energy, resilience and overall vitality.

  • Ageing is driven by multiple cellular processes that can be supported through targeted nutrition
  • Healthy cellular function underpins energy, focus and resilience
  • Early support helps maintain long-term wellbeing

Many products focus on single ingredients or low doses that can’t meaningfully influence cellular processes. MUTO is built differently - clinically dosed, multi-pathway, most bio-available form of each ingredient, and purposely engineered for measurable impact.

  • Most supplements use low doses and fillers like magnesium stearate that add bulk, not benefit
  • Many formulas prioritise trends over evidence, with no real scientific or PhD-led oversight
  • MUTO is clinically dosed, third-party tested and free from unnecessary fillers - built on real longevity science

Our formulation is guided by peer-reviewed research and designed by a PhD in Longevity Nutrition, ensuring each ingredient has a clear role within the broader biology of ageing.

  • Guided by longevity science to strengthen cellular energy and daily recovery
  • Powered by clinically studied, fully traceable ingredients
  • Designed to help you feel more resilient - today and over the long term

THIS IS WHAT AGEING & RESILIENCE LOOKS LIKE AT THE CELLULAR LEVEL

Over time, energy declines, damage accumulates and repair slows. MUTO is designed to support the systems that age first.

When your cells function efficiently

TIME

Time arrow

AGEING IS GRADUAL - BUT CUMULATIVE, AND MUTO SUPPORTS THE SYSTEMS WHICH DRIVE IT AT A CELLULAR LEVEL

As cellular systems decline with age

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

THIS IS WHAT AGEING & RESILIENCE LOOKS LIKE AT THE CELLULAR LEVEL

Over time, energy declines, damage accumulates and repair slows. MUTO is designed to support the systems that age first.

When your cells function efficiently

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

As cellular systems decline with age

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

YOU EXPERIENCE:

  • Sustained energy throughout the day
  • Faster recovery from training, stress and travel
  • Clearer focus & mental sharpness
  • Stable mood & motivation
  • Resilient metabolism and flexibility
  • Better long-term healthspan foundations

A UNIQUE, MULTI-PATHWAY FORMULA TO SUPPORT DAILY RESILIENCE

Designed to impact multiple ageing pathways for measurable improvements in cellular health.

Cellular Energy Complex
(NAD+ Pathway)

Cellular Energy Complex
(NAD+ Pathway)

Cellular Energy & Mitochondrial Function

Supports cellular energy production and mitochondrial function linked to daily performance.

Primary Function

Natural energy production by helping your cells repair and function efficiently.

Key Ingredient

Nicotinamide Riboside

300MG

Methyl B Vitamin Complex

100% NRV

Cellular Protection Complex (Antioxidants)

Cellular Protection Complex (Antioxidants)

Oxidative Stress Defence & Cellular Protection

Supports cellular protection against oxidative stress linked to long-term cellular health.

Primary Function

Protect your cells from everyday stress, supporting long-term cellular health.

Key Ingredient

Pterostilbene

100MG

Grape Seed Extract

150MG

Cellular Renewal Complex (Senolytics)

Cellular Renewal Complex (Senolytics)

Senescent Cell Clearance & Cellular Renewal

Supports the clearance of older, less efficient cells linked to healthier cellular function over time.

Primary Function

Helps to clear out older, less efficient cells which have harmful effects on healthy cells.

Key Ingredient

Fisetin

100MG

Quercetin

250MG

Metabolic Efficiency Complex

Metabolic Efficiency Complex

Mitochondrial Efficiency & Energy Utilisation

Supports efficient mitochondrial energy use linked to improved metabolic function and endurance.

Primary Function

Healthy mitochondrial function to help your body use energy more effectively.

Key Ingredient

Curcumin & Piperine

200 & 20MG

Methyl B Vitamin Complex

100% NRV

Inflammation Balance Complex

Inflammation Balance Complex

Inflammatory Balance & Cellular Resilience

Supports a balanced inflammatory response linked to overall cellular resilience and wellbeing.

Primary Function

Helps maintain a balanced inflammatory response to support overall wellbeing.

Key Ingredient

Curcumin & Piperine

200 & 20MG

Grape Seed Extract

150MG

DNA STABILITY & METHYLATION COMPLEX

DNA STABILITY & METHYLATION COMPLEX

Epigenetic Support & Cellular Repair

Supports healthy methylation and DNA integrity linked to long-term cellular function.

Primary Function

Healthy DNA processes that help maintain long-term cellular stability and ageing.

Key Ingredient

Methyl B Vitamin Complex

100% NRV

Vitamins D3 & K2

1000IU & 80µg

WHY THIS MULTI-PATHWAY APPROACH MATTERS

Ageing biology is interconnected.

Supporting energy production without oxidative protection is incomplete.


Boosting NAD+ without metabolic or inflammatory support is short-lived. Targeting one pathway ignores how cells actually function.


MUTO’s six-complex structure reflects how modern longevity science understands ageing - as a network of interacting systems, not a single switch.

YOUR ESSENTIALS FOR HEALTHY AGEING

A focused blend of scientifically studied ingredients designed to support key pillars of longevity: cellular energy, mitochondrial function, inflammation balance, oxidative defence and metabolic efficiency.

Nicotinamide Riboside (NR)

DOSAGE: 300MG

A form of Vitamin B3 that helps your body create NAD⁺ - the molecule your cells use for energy and repair.

Cellular Energy · DNA Stability

  • Fuels cellular energy to support daily vitality and performance
  • Reinforces repair processes linked to healthy ageing
  • Included at a dose diet alone cannot deliver

Quercetin

DOSAGE: 250MG

A natural flavonoid that supports antioxidant activity, reduces oxidative stress and strengthens overall cellular resilience.

Cellular Renewal · Protection

  • Strengthens cellular resilience against everyday stress
  • Encourages healthier cell function and turnover over time
  • Selected for broad, whole-cell protection

Grape Seed Extract

DOSAGE: 200MG

A concentrated source of antioxidants (OPCs) that help protect against oxidative stress and support circulation.

Cellular Protection · Inflammation Balance

  • Shields cells from oxidative stress that accelerates ageing
  • Supports circulation and cellular integrity
  • Chosen for its highly concentrated antioxidant power

Pterostilbene

DOSAGE: 100MG

A powerful plant antioxidant similar to resveratrol, but more absorbable and longer-lasting in the body.

Cellular Protection

  • Provides long-lasting antioxidant defence at the cellular level
  • Helps protect cells from cumulative environmental stress
  • Included for superior absorption compared to similar compounds

Fisetin

DOSAGE: 100MG

A natural compound found in fruits like strawberries that helps the body clear out old, worn-out cells.

Cellular Renewal (Senolytics)

  • Supports the removal of older, inefficient cells
  • Promotes cleaner, more efficient cellular renewal
  • Selected for its role in long-term cellular health

METHYL Vitamin B Complex

DOSAGE: 100% NRV

Essential B-vitamins that help the body turn food into usable energy and support brain and metabolic function.

Energy · Metabolic Efficiency · DNA Stability

  • Optimises energy production and nutrient utilisation
  • Supports brain, metabolic, and methylation pathways
  • Delivered in active forms for better absorption and effectiveness

Vitamin D3 + K2

DOSAGE: 1000IU & 80µg

Two vitamins that work together for immunity, bone health and proper calcium use in the body.

STRUCTURAL INTEGRITY · IMMUNE RESILIENCE · CELLULAR LONGEVITY

  • Supports calcium metabolism for healthy bones and skeletal strength
  • Contributes to normal immune function and cellular defence
  • Helps maintain vascular integrity by supporting proper calcium distribution

Curcumin + Piperine

DOSAGE: 200MG & 20MG

Curcumin from turmeric supports inflammation balance; piperine from black pepper improves absorption.

INFLAMMATION BALANCE · METABOLIC EFFICIENCY · CELLULAR PROTECTION

  • Helps maintain a balanced inflammatory response
  • Supports efficient metabolic and mitochondrial function
  • Contributes to cellular protection against oxidative stress

To learn more about our ingredients and the supporting studies, visit our scientific resource library

scientific resource library

WE ARE COMMITTED TO CREATING THE HIGHEST QUALITY PRODUCTS

Quality begins long before the capsule.

Every stage of our production is guided by pharmaceutical-grade standards and rigorous testing:

formulation

Our formulas are excipient- and filler-free, built on insights from 300+ human clinical studies and dosed at levels shown to be effective. Each ingredient is selected to work synergistically across six key cellular pathways, supporting energy, repair, and long-term cellular health - not just in isolation, but as an integrated system.

formulation

BIO-AVAILABILITY

What matters is what your body can actually use. Our formulas prioritise bioavailable ingredient forms - choosing pterostilbene over resveratrol, methylated B vitamins, and clinically validated delivery to support real cellular uptake.



This approach is informed by human research showing oral NR can significantly increase NAD⁺ levels by 51% within two weeks, reinforcing our focus on effectiveness, not just ingredients on a label.

BIO-AVAILABILITY

Ingredient verification

Every ingredient is rigorously verified for identity, purity, and potency before it enters our supply chain. We work only with trusted UK-based partners and fully traceable sources to ensure consistency, quality, and safety from the very first step.

Ingredient verification

UK production

All MUTO products are manufactured in the UK to pharmaceutical-grade standards, with strict quality controls in place at every stage. This ensures precision, batch-to-batch consistency, and uncompromising quality you can trust.

UK production

Third-party testing

Each batch is independently tested to confirm ingredient accuracy, dosage, and freedom from contaminants. This extra layer of verification ensures what’s on the label is exactly what you take - every time.

Third-party testing

Third-party testing

Our formulas are informed by 300+ human clinical trials and supported by our own investment in randomised clinical trials with UK- and Australia-based institutions. This level of clinical commitment is rare in the supplement industry - and it’s a standard we choose to set and uphold.

Third-party testing

SCIENTIFIC RESOURCES

Transparent science. Fully referenced.

Every ingredient and pathway in MUTO is selected from peer-reviewed scientific research, prioritising human data, mechanistic relevance, and clinically meaningful dosing.

We believe longevity science should be open, verifiable, and accessible.

Our research library includes:

  • Peer-reviewed studies on NAD+ metabolism, mitochondrial function, and cellular ageing
  • Human and pre-clinical research on senolytics, polyphenols, and oxidative defence
  • Evidence supporting inflammation balance, metabolic efficiency, and DNA stability
  • Ingredient-specific citations linked directly to each biological pathway

You don’t have to take our word for it - the science is there to review.

SCIENTIFIC RESOURCE LIBRARY

CELLULAR BENEFITS BUILD BEFORE YOUR EVEN FEEL IT

Because lasting, meaningful change starts deep within.

HOUR 04

HOUR 04

CELLULAR UPTAKE BEGINS

Your cells begin absorbing key nutrients, initiating support for energy, clarity and focus. Early cellular activity helps lay the groundwork for more stable daily vitality.

DAY 02

DAY 02

DEEP NOURISHMENT STARTS

Foundational nutrients begin supporting core pathways involved in energy, inflammation, and cellular repair. You may feel subtly more balanced, steady and nourished from within.

DAY 30

DAY 30

NOTICEABLE DIFFERENCES & ADAPTATION

Cellular systems start adapting. Many people experience smoother energy, clearer thinking, better recovery, and more consistent day-to-day performance. Healthy rhythms begin to feel more natural.

DAY 60

DAY 60

VISIBLE IMPROVEMENTS YOU CAN FEEL

As renewal and protection pathways compound, you may notice clearer skin, deeper resilience, improved mood stability, and easier recovery. Daily vitality feels stronger and more reliable.

DAY 120

DAY 120

MEASURABLE SHIFTS & ANTI-AGEING SUPPORT

Multiple longevity pathways are now actively supported — from inflammation balance to cellular energy, renewal and DNA stability. Many users report feeling noticeably younger, more resilient and more energised.

DAY 360

DAY 360

STRONGER HEALTHSPAN & SLOWER BIOLOGICAL AGEING

Long-term consistency supports deeper changes in cellular function. You may experience stronger overall wellbeing, enhanced vitality, and signs of slower biological ageing — helping you feel healthier, sharper and more resilient year after year.

FREQUENTLY ASKED QUESTIONS

See all FAQs

What ingredients does MUTO LONGEVITY contain?

MUTO Longevity contains 10 clinically backed, scientifically dosed and fully traceable ingredients, individually tested for their authenticity and quality. The ingredients are: Nicotinamide Riboside Chloride, Pterostilbene, Grape Seed Extract, Fisetin, Quercetin, Curcumin, Piperine, Vitamin D3, Vitamin K2and a methylated Vitamin B Complex.

Is MUTO LONGEVITY safe to consume for children or pregnant women?

MUTO Longevity is recommended for use over the age of 18, and should be avoided if you are pregnant or breastfeeding.

When should I take Muto LONGEVITY?

For optimal bio-availability and efficacy, it is recommended to take MUTO Longevity with your first meal of the day. This meal should contain a healthy fat source to support increase absorption of nutrients, which may include avocado, olive oil, eggs, oily fish, nuts or nut butter.

Does Muto Longevity contain allergens?

MUTO Longevity is GMO and allergen free.

Is Muto LONGEVITY Vegan friendly?

MUTO Longevity is vegan friendly, and is safe to consume as part of a plant based diet.

What if Muto LONGEVITY doesn’t work immediately?

MUTO Longevity’s benefits build over time and everyone will have a unique experience. Muto’s formulation is clinically proven to nourish your cells with the nutrients they need to function optimally and provide vitality. We suggest taking Muto for at least three months, and tracking biometric data using wearable health technology devices to understand the difference it has on your internal and external well-being.

Is Muto LONGEVITY proven to work?

MUTO Longevity is a food supplement and, therefore, cannot make medical claims. Our unique formula, expertly crafted by our longevity PhD founder, contains clinically proven ingredients that support vitality, optimal well-being and longevity. MUTO Longevity is proudly third-party tested for purity and safety.

See all FAQs