In the ever-evolving landscape of longevity supplements, nicotinamide riboside (NR) and pterostilbene have garnered increasing attention for their potential to support healthy ageing. As researchers continue to uncover the mechanisms behind cellular health and longevity, these compounds have become key players in the quest to optimise health span. But do they truly deliver on their promises?
The Role of NAD+ in Longevity
Nicotinamide riboside (NR) is a precursor to nicotinamide adenine dinucleotide (NAD+), a vital coenzyme that plays a central role in cellular metabolism and energy production. NAD+ levels naturally decline with age, leading to impaired mitochondrial function, reduced cellular repair, and an increased risk of age-related conditions. By supplementing with NR, it is possible to boost NAD+ levels, potentially mitigating some of the detrimental effects of ageing.
Pterostilbene: A Powerful Antioxidant
Pterostilbene is a polyphenol structurally similar to resveratrol but with superior bioavailability. Found in blueberries and certain other plants, pterostilbene is known for its potent antioxidant and anti-inflammatory properties. Research suggests it may activate sirtuins, a family of proteins linked to longevity, and support healthy cellular function.
Synergistic Effects for Longevity
When combined, NR and pterostilbene may offer complementary benefits for cellular health. NR increases NAD+ levels, supporting mitochondrial function and energy production, while pterostilbene enhances antioxidant defences and may improve sirtuin activity. Together, these compounds have the potential to improve resilience to oxidative stress, reduce inflammation, and promote longevity at a cellular level.
Longevity Supplements in the UK
The UK market for longevity supplements has expanded significantly, with NR and pterostilbene among the most sought-after ingredients. As with any supplement, it is essential to choose high-quality, third-party-tested products to ensure purity and efficacy. Consulting with a healthcare professional before starting any new regimen is always recommended, particularly for those with underlying health conditions.
Can NR and Pterostilbene Extend Healthspan?
While early research is promising, more clinical studies are needed to fully understand the long-term effects of NR and pterostilbene on human healthspan. Current evidence suggests they may support cellular repair, mitochondrial function, and oxidative stress reduction, all of which contribute to healthier ageing. However, lifestyle factors such as diet, exercise, and sleep remain crucial pillars in the pursuit of longevity.
Final Thoughts
NR and pterostilbene represent exciting developments in the field of longevity and ageing. By supporting NAD+ levels and cellular health, these compounds may offer valuable benefits for those looking to maintain vitality and extend healthspan. As scientific research continues to evolve, these longevity supplements could become key tools in promoting healthier ageing in the UK and beyond.
